Efficacy of magnesium sulphate in myofascial trigger point injections in chronic neck pain - A randomised controlled trial
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- Numeric Rating Scale for pain
研究概览
简要总结
Myofascial pain syndrome is a common problem for chronic neck and back pain in general population. Different treatment modalities like Dry needling, Trigger point injections, Transcutaneous Electrical Nerve Stimulation exists, but among these Trigger Point Injections is widely accepted method. In trigger point iInjections Local anaesthetics, Steroids, Botulinum toxins has been used previously. Recent study shows Magnesium as a new promising alternative. Moreover, Magnesium Sulphate is cheaper, easily available and have lesser side effects when used as an injectate in Trigger Point Injection. Magnesium can be beneficial as it acts as a vasodilator which leads to wash away accumulated toxins like prostaglandin, bradykinin etc. It also acts as muscle relaxant and inhibits pre-synaptic Acetylcholine release from neuromuscular junction and sympathetic junction Therefore, our study aims to prove that Magnesium Sulphate can be used as an alternative injectate in Trigger Point Injection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Neck pain more than 3 months 2.Age more than 18years 3.Definitive diagnosis of myofascial pain syndrome of neck muscles with identification of trigger points defined by presence of one or more taut bands in muscle, focal tenderness within these taut bands, local or referred pain on palpation or gentle snapping palpation elicits a twitch response.
排除标准
- •1.Patients not giving consent 2.Any painful conditions of neck and back muscles other than myofascial pain syndrome like fibromyalgia, spondylosis, cervical radiculopathy, vertrebrobasilar insufficiency 3.Known allergy to local anaesthetics or magnesium sulphate 4.History of prior invasive procedure in neck muscle.
结局指标
主要结局
Numeric Rating Scale for pain
时间窗: 3months
次要结局
- Neck disability index(1month and 3 months)
- Numerical Rating Scale for pain(14days and 1month)
- Patient satisfaction score(1month and 3 months)
- Neck movement using goniometer(1month and 3 months)
- Pain pressure threshold using algometer(1month and 3months)