Pain in adults with Down syndrome.
- Conditions
- PainDown syndromeCognitionDementiaPainDown syndromeCognitionDementia
- Registration Number
- NL-OMON21264
- Lead Sponsor
- Performer: VU university, Department of Clinical Neuropsychology, The Netherlands.Main investigator: Nanda de Knegt (MSc.)Doctoral thesis supervisors: prof. dr. Scherder and prof. dr. Evenhuis.METC permission: submitted in May 2011, in progress.
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 315
Inclusion Criteria
Control group: N= 105
1. Aged 18 years or older;
Exclusion Criteria
Control group:
1. Diagnosis of intellectual disability;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study parameters are:<br /><br>1. The difference in pain experience between the control group and Down syndrome group;<br /><br>2. The difference in pain experience between Down syndrome adults without versus with indications for dementia;<br /><br>3. The difference in the relationship between pain and cognitive functioning comparing Down syndrome adults without versus with dementia;<br /><br>4. The difference in pain experience, cognitive functioning, and the relationship between pain experience and cognitive functioning comparing Down syndrome adults without versus with ApoE e4 allele.
- Secondary Outcome Measures
Name Time Method