Physical Exercise and Dairy Probiotics in Childhood Cancer Survivors
- Conditions
- Acute Lymphoblastic Leukemia, Pediatric
- Registration Number
- NCT05939791
- Lead Sponsor
- Comenius University
- Brief Summary
The goal of this clinical trial is to to compare the structure of the intestinal microbiome between children shortly after treatment for acute lymphoblastic leukemia (1-3 years after cancer treatment) and healthy controls. And then to provoke a positive shift of bacterial diversity by physical activity and probiotics in cured pediatric oncology patients with persistent gut microbiome disruptions.
The main question\[s\] it aims to answer are:
* Are differences in bacterial richness between healthy controls and pediatric oncology patients ≥12 months after cancer treatment apparent?
* Has the combination of physical exercise and probiotics had a positive influence on the structure of the gut microbiome in childhood cancer survivors in remission? Two times per week of physical activity and daily dairy consumption with probiotics will be required of participants for eight weeks.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 29
- children previously diagnosed and treated for acute lymphoblastic leukemia in remission between 1 and 3 years
- acute respiratory infection during intervention
- more than 20% skipped exercise training sessions
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method The shift of gut microbiome by physical exercise and consumption of dairy probiotics. 8 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Pediatric Hematology National Institute of Children's Diseases Bratislava
🇸🇰Bratislava, Slovakia
Department of Pediatric Hematology National Institute of Children's Diseases Bratislava🇸🇰Bratislava, Slovakia