跳至主要内容
临床试验/NCT04988958
NCT04988958已完成不适用

Radical Versus Conservative Surgical Treatment of Liver Hydatid Cysts: A Propensity Score Matching Analysis

Université de Sousse0 个研究点目标入组 914 人开始时间: 2000年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
914
主要终点
recurrence of hydatic cyst

研究概览

简要总结

The management of liver hydatid cysts (LHC) is controversial. Surgery remains the basic treatment, and can be divided into radical and conservative approaches. The purpose of this study was to compare the outcome of radical and conservative surgery (CS) in the treatment of LHC and to evaluate the efficiency and safety of radical surgery (RS).

详细描述

The management of liver hydatid cysts (LHC) is controversial. Surgery remains the basic treatment, and can be divided into radical and conservative approaches. The purpose of this study was to compare the outcome of radical and conservative surgery (CS) in the treatment of LHC and to evaluate the efficiency and safety of radical surgery (RS).

Data from all patients with LHC treated in Sahloul Hospital, between January 2000 and December 2019, were retrieved from a retrospective database. To minimize selection bias, propensity score matching (PSM) was performed, based on variables representing patient characteristics and operative risk factors.

RS especially total pericystectomy had fewer postoperative complications and lower recurrence rate compared to CS. RS may be the preferred procedure for LHC if the expertise is available.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
14 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age over 14 years old.
  • Patients presenting liver hydatid cyst .

排除标准

  • age less than 14 years old.
  • Patients presenting other localization of hydtic cyst , than the liver.
  • calcified cysts.
  • patients with incomplete medical records.
  • patients who were lost to follow up.

结局指标

主要结局

recurrence of hydatic cyst

时间窗: 2 years

recurrence of hydatid cyst after surgery

次要结局

未报告次要终点

研究者

发起方
Université de Sousse
申办方类型
Other
责任方
Principal Investigator
主要研究者

ammar houssem

clinical professor

Université de Sousse

相似试验