Resection for Multiple Hepatocellular Carcinomas (HCC)

Not Applicable

Completed

• Conditions: Hepatocellular Carcinoma; Multiple Tumors; Cirrhosis

• Registration Number: NCT01387061
• Lead Sponsor: University of Milan

Brief Summary

Surgical resection in patients with multiple hepatocellular carcinomas (HCC) remains controversial. The aim of this study was to investigate the outcome of a consecutive cohort of patients resected for multiple HCC, without macrovascular invasion, in order to identify clinically reliable parameters to select patients for surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2001-06
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Study First Submitted: 2011-06-29
• Study First Submitted QC: 2011-07-01
• Study First Posted: 2011-07-04
• Status Verified: 2011-09
• Last Update Submitted: 2011-09-18
• Last Update Posted: 2011-09-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 87

Inclusion Criteria

• patients with multiple HCC without macrovascular invasion on liver cirrhosis

Exclusion Criteria

• macrovascular invasion;
• normal liver;
• distant or lymphnodes metastasis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Overall survival plus multivariate analysis	10 years	The primary endpoint of the study was the overall survival of patients resected for multiple HCC, and the univariate and multivariate analyses of prognostic factors for overall survival.

Secondary Outcome Measures

Name	Time	Method
Disease-free survival	10 years	The secondary endpoint was the disease-free survival.

Trial Locations

Locations (1)

University of Milan IRCCS Istituto Clinico Humanitas; 🇮🇹 Rozzano, Milan, MI, Italy

University of Milan IRCCS Istituto Clinico Humanitas

🇮🇹Rozzano, Milan, MI, Italy