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Clinical Trials/NCT02479152
NCT02479152
Completed
Not Applicable

The Haemodynamic Effects of Mechanical Standard and Active External Chest Compression-decompression During Out-of-hospital Cardiopulmonary Resuscitation

Physio-Control1 site in 1 country126 target enrollmentApril 2015
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ConditionsCardiac Arrest

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiac Arrest
Sponsor
Physio-Control
Enrollment
126
Locations
1
Primary Endpoint
Hemodynamics measured as EtCO2
Status
Completed
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The aim of this randomized out-of-hospital cardiopulmonary resuscitation study is to investigate haemodynamics generated by the standard mechanical external chest compression device (LUCAS™ 2) compared to a new version generating chest compressions and active decompression above the initial starting position of the suction cup (LUCAS™ 2AD).

Detailed Description

Based on randomization patients will receive standard or active compression decompression chest compression and the haemodynamic effects will be compared.

Registry
clinicaltrials.gov
Start Date
April 2015
End Date
April 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Physio-Control
Responsible Party
Principal Investigator
Principal Investigator

Lars Wik

MD, PhD

Ullevaal University Hospital

Eligibility Criteria

Inclusion Criteria

  • •Unexpected adult out-of-hospital non-traumatic cardiac arrest where an attempt of resuscitation is considered appropriate in:
  • •Patients 18 years or older

Exclusion Criteria

  • •Traumatic cardiac arrest
  • •Age believed to be less than 18 years
  • •Known pregnancy
  • •Victim not to be resuscitated (DNR orders)
  • •Internals in prison
  • •Included once in the study already
  • •To Small/Large patients
  • •Sustained ROSC occurring before the LUCAS™ 2 or LUCAS™ 2-AD can be applied to the patient, such that further CPR is not needed

Outcomes

Primary Outcomes

Hemodynamics measured as EtCO2

Time Frame: During 30 minutes of CPR

Secondary Outcomes

  • Intra arterial blood pressures,(During 30 minutes of CPR)
  • Oximetry,(During 30 minutes of CPR)
  • ROSC (Return of spontaneous circulation)(During CPR)
  • safety(During 30 minutes of CPR)

Study Sites (1)

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