An observational study to assess & predict the in-patient course, risk of readmission and mortality for patients hospitalised for or with Heart Failure

Hull and East Yorkshire Hospitals NHS Trust0 个研究点目标入组 1,145 人开始时间: 2013年4月18日最近更新: 2021年4月12日

适应症

试验速览

•Inclusion Criteria for the Risk Stratification Component:
•1. Age >18 years
•2. In hospital
•3. Usual residence is in the catchment region for Hull & East Yorkshire Hospitals Trust (this enables efficient follow-up)
•4.1. Treated with loop diuretics Or
•4.2.Clinical diagnosis of heart failure
•5. Willing and able to provide informed consent
•Additional Inclusion Criteria for the Monitoring Component of the Study:
•Heart failure as a dominant diagnosis meaning that
•1. There is objective evidence of cardiac dysfunction as evidenced by a least ONE of the following:
•1.1. Left ventricular ejection fraction <= 40%
•1.2. Left atrial dimension >4.0 cm (or >2.5 cm/m in height)
•1.3. NT ? ProBNP > 400pg/ml (>47.3pmol/L (or BNP >150 pg/ml) if in sinus rhythm or >1,200pg/ml (or BNP >450pg/ml) if in atrial fibrillation
•2. The patient is receiving loop diuretics
•3. Target Gender: Male & Female ; Lower Age Limit 80 years

•Unable to understand and comply with protocol or to give informed consent. There are no other exclusion criteria for the risk stratification study.
•Additional Exclusion Criteria for the Monitoring Component of the Study:
•The duration of admission is likely to be determined by the need for treatment other than for heart failure (for instance, patients with infective endocarditis, major stroke disability or major cognitive impairment will be excluded).

发起方

Hull and East Yorkshire Hospitals NHS Trust