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临床试验/NCT06630988
NCT06630988进行中(未招募)不适用

Diagnostic and Management of Hand Infection: a Retrospective Cohort in a Tertiary Care Center.

Hospices Civils de Lyon1 个研究点 分布在 1 个国家目标入组 1,400 人开始时间: 2024年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
1,400
试验地点
1
主要终点
Percentage of treatment failure during the management of hand infections.

研究概览

简要总结

Primary or secondary (post-traumatic infections, notably related to bites, wounds, etc.) infections of the hand are very common situations, even if the epidemiology is poorly understood. For example, hand bite injuries represent 1.2 million referrals to the healthcare system per year in the United States. Their nosological framework extends from simple infections of the skin and soft tissues such as whitlows, to potentially severe deep damage such as arthritis and osteitis, or phlegmons of the tendon sheaths. The diagnostic approach is not consensual, and the contribution of additional biological parameters (inflammatory syndrome) and morphological investigations (x-rays, ultrasound, CT-scan or MRI) is not codified. Microbiology seems dominated by Staphylococcus aureus, but few studies have precisely described the microbial etiology. Consequently, probabilistic antibiotic therapy and the need to take bacteriological samples for secondary adaptation are not standardized. Likewise, surgical strategies (abstention, systematic washing or depending on evolution) remain operator dependent. We consequently aim to described diagnostic, management and related outcomes or hand infections in a specialized tertiary care center.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • all patient ≥ 18
  • yo followed-up for a hand infection in our tertiary care center
  • from 01/01/2014 to 31/12/2023, including
  • tendinous infections
  • septic arthritis

排除标准

  • osteomyelitis

结局指标

主要结局

Percentage of treatment failure during the management of hand infections.

时间窗: between 01/01/2014 and 31/12/2023.

Treatment failure will be defined as infection persistence or relapse, need of unplanned surgery for septic reason or infection-related death.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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