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Establishment and validation of high-throughput methods for biomarker development in SCA1/2 and 3

Conditions
G00-G99
Diseases of the nervous system
Registration Number
DRKS00020219
Lead Sponsor
niversitätsklinikum Tübingen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
300
Inclusion Criteria

SCA3 disease

Exclusion Criteria

No study consent

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Measuring if disease protein itself is a potential molecular marker for SCA3 disease progression.<br>Primary outcome: ataxin-3 protein as progression marker: Yes/no
Secondary Outcome Measures
NameTimeMethod
secondary aims are clinincal data (like age at onset, disease duration, clinical scores like SARA, INAS)<br><br>No endpoints are defined because each measurement points stands alone.
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