CTRI/2023/10/058414
Recruiting
N/A
Evaluation of effect of genetic polymorphism on antidiabetic medication in Indian patients with Type 2 Diabetes for development of a pharmacogenomic test for T2DM patients - NI
Chellaram Diabetes Research Centre0 sites0 target enrollmentTBD
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Health Condition 1: E119- Type 2 diabetes mellitus without complications
- Sponsor
- Chellaram Diabetes Research Centre
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects from Indian population diagnosed with Type 2 diabetes according to the criteria of the American Diabetes Association.
- •Subjects having with HbA1c in the range of 7\.5–12% and either on monotherapy or combination therapy on antidiabetic drugs.
- •Subjects over 18 years old and below 60 years
- •Subjects who agree with the written informed consent to participate in the study
Exclusion Criteria
- •Other than Indian ethnicity
- •Under 18 years old
- •Pregnant or lactating women
- •Patients with malignancies, and chronic kidney disease stage 3–5, liver cirrhosis
- •Presently suffering from congestive heart failure requiring pharmacologic treatment (medical history)
- •Past history of urinary or gastric retention or narrow\-angle glaucoma
- •Presently severe anaemia
- •Taking a medication that could confound study results, such as known substrates or inhibitors of OCT3 and MATE1, such as cimetidine.
- •They do not provide consent to participate in the study.
Outcomes
Primary Outcomes
Not specified
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