Novel Risk Factors of Atrial Fibrillation in Patients With Chronic Heart Failure
- Conditions
- Heart Failure
- Registration Number
- NCT02655185
- Lead Sponsor
- Yangzhou No.1 People's Hospital
- Brief Summary
The purpose of this study is to determine whether lipid levels are related with incidence of atrial fibrillation in Patients with chronic heart failure.
- Detailed Description
Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice. Chronic Heart failure (CHF) has become a major clinical and public health problem. Both AF and CHF often co-exist and complicate each other's administration.Several risk factors have been demonstrated to be associated with the risk of AF in Patients with CHF.
Lopez et al. found that higher levels of low-density lipoprotein cholesterol (LDLc) and total cholesterol were associated with a lower incidence of AF independently of other risk factors from the Atherosclerosis Risk in Communities (ARIC) study.
Thus the purpose of this study is to determine whether lipid levels are related with incidence of atrial fibrillation in Patients with chronic heart failure. This study maybe provide a novel opinion on the prevention of AF in patients with CHF.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
- Clinical diagnosis of chronic heart failure
- Use of statins
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of participants with newly emerging atrial fibrillation as assessed by electrocardiogram three years
- Secondary Outcome Measures
Name Time Method Cardiovascular mortality three years Worsing heart failure assessed by decreased NYHA class and left ventricular ejection fraction three years rate of rehospitalization three years