Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing Among Hypertensive and Non-Hypertensive Patients
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Healing of the extraction socket
研究概览
简要总结
There is no evidence based guidelines on using saline rinses for post extraction oral care among hypertensives. Similarly, benefit of orally dissolved topical analgesics in addition to orally administered analgesic is questionable.
详细描述
Objective
To compare the post dental extraction healing among subjects who took simple analgesic tablets dissolved in water versus those who used saline rinses post operatively.
Methods: A study will be done among patients who underwent dental extractions at AKHSP dental clinic, Karachi, Pakistan. Carious, periodontally mobile, traumatized or broken down teeth among 20-70 years old in either gender will be included.
In addition to the routine prescription of antibiotics and oral analgesics, the hypertensive subjects (n=20) will be advised to take dissolved Aspirin tablet as an oral care while non-hypertensive will be divided into two sub groups (n=20 each), advised saline mouth rinses or dissolved Aspirin for 5 days, respectively.
The outcome (healing of the extraction socket) will be evaluated 7 days from the day of extraction on an ordinal scale.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Carious, periodontally mobile, traumatized or broken down teeth needing extraction
- •Age 20-70 years, both genders
排除标准
- •Osteoporosis, metabolic bone disease etc.
- •Radiation therapy or chemotherapy.
研究组 & 干预措施
hypertensives on Aspirin mouthwash
干预措施: Aspirin Powder (Drug)
non-hypertensives on Aspirin mouthwash
干预措施: Aspirin Powder (Drug)
hypertensives on Saline mouthwash
干预措施: Normal saline (Drug)
结局指标
主要结局
Healing of the extraction socket
时间窗: Seven days from the day of extraction
1. = "healed or healing well" 2. = "incomplete healing but progressing" 3. = "poorly healed open margins and readily bleeding"
次要结局
未报告次要终点
研究者
Farhan Raza Khan
Associate Professor
Aga Khan University