Metabolic control with Glucose-Insulin-Potassium infusion in acute myocardial infarctio

Completed

• Conditions: Acute myocardial infarction; Circulatory System; Myocardial infarction

• Registration Number: ISRCTN08189331
• Lead Sponsor: Isala Klinieken (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-02-26
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 900

Inclusion Criteria

1. Acute myocardial infarction diagnosed by:
1.1. Chest pain suggestive for acute myocardial infarction
1.2. Symptom-onset less than six hours after hospital admission
1.3. Electrocardiogram (ECG) with ST-T segment elevation more than 1 mV in two or more leads
2. Patients are eligible for either primary coronary angioplasty or thrombolysis
3. Patient who has given his or her informed consent to take part in the study

Exclusion Criteria

1. Unwillingness to participate
2. Presence of heart failure (either one of these symptoms):
2.1. Heart rate more than 90 beats/minute
2.2. Systolic blood pressure less than 100 mmHg with anterior myocardial infarction
2.3. Killip class greater than or equal to II (third heart sound, greater than or equal to hand-wide rales)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
30-day mortality (death from any cause and cardiovascular death).

Secondary Outcome Measures

Name	Time	Method
1. One-year mortality<br>2. Analysis of pre-specified subgroups