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临床试验/NCT05689138
NCT05689138进行中(未招募)不适用

SCREENING ORAL AND GUT MICROBES AS A MORE ACCURATE NON-INVASIVE TOOL FOR PANCREATIC CANCER EARLY DETECTION: A POPULATION-BASED CASE-CONTROL STUDY IN CHINA

Peking Union Medical College Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2020年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
100
试验地点
1
主要终点
microbial features by 16s rRNA sequencing

研究概览

简要总结

Pancreatic cancer (PCA) is a leading death-related cancer. There is an urgent need for accurate, noninvasive diagnostic options in the early detection of pancreatic cancer (PCA), since delayed diagnosis increases the risk of metastasis and recurrence. In this study, by analyzing gut and fecal microbial data among the pancreatic versus healthy populations, we aim to establish an early detection tool to improve PCA detection, and to explore potential diagnostic biomarkers.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • PCA Newly diagnosed pancreatic cancer patients; No symptoms of jaundice; Did not yet receive any treatment
  • NC Individuals who were undergoing routine screenings or physical examination

排除标准

  • 未提供

结局指标

主要结局

microbial features by 16s rRNA sequencing

时间窗: within 180 days

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dai Menghua

Professor

Peking Union Medical College Hospital

研究点 (1)

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