Using Digestive Microbial Information to Enhance the Early Detection of Pancreatic Cancer
Active, not recruiting
- Conditions
- Pancreatic Cancer
- Interventions
- Other: Oral and Fecal Sample Collection
- Registration Number
- NCT05689138
- Lead Sponsor
- Peking Union Medical College Hospital
- Brief Summary
Pancreatic cancer (PCA) is a leading death-related cancer. There is an urgent need for accurate, noninvasive diagnostic options in the early detection of pancreatic cancer (PCA), since delayed diagnosis increases the risk of metastasis and recurrence. In this study, by analyzing gut and fecal microbial data among the pancreatic versus healthy populations, we aim to establish an early detection tool to improve PCA detection, and to explore potential diagnostic biomarkers.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
PCA Newly diagnosed pancreatic cancer patients; No symptoms of jaundice; Did not yet receive any treatment
NC Individuals who were undergoing routine screenings or physical examination
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description NC Oral and Fecal Sample Collection normal control PCA Oral and Fecal Sample Collection pancreatic cancer patients
- Primary Outcome Measures
Name Time Method microbial features by 16s rRNA sequencing within 180 days
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
PUMCH
🇨🇳Beijing, Beijing, China