Evaluation of Platelet Rich Fibrin Use in the Treatment of Dry Socket.
Overview
- Phase
- N/A
- Intervention
- PRF application
- Conditions
- Alveolar Osteitis
- Sponsor
- Medical University of Lodz
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Influence of treatment on bacteria levels in wounds
- Last Updated
- 5 years ago
Overview
Brief Summary
The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.
Detailed Description
The main objective was to compare the effects of using two different methods in the treatment of dry socket (alveolar osteitis), which is a postoperative complication of dental extraction. The first was Nipas, applied, if dry socket was diagnosed following a tooth extraction. In case of subsequent extraction of homonymous tooth and reoccurrence of dry socket, patients were treated with application of PRF.
Investigators
Eligibility Criteria
Inclusion Criteria
- •no known medical history of abnormal platelet counts,
- •patients with symmetric teeth qualified for extraction,
Exclusion Criteria
- •patients treated previously for existing dry socket,
- •patients allergic to acetylsalicylic acid ,
- •systemic diseases,
- •pregnancy,
- •lactation,
- •drugs known to affect the number or function of platelets,
- •abnormal platelet counts,
Arms & Interventions
PRF application
Patients with alveolar osteitis in which PRF application was performed.
Intervention: PRF application
Aspirin application
Patients with alveolar osteitis in which Nipas was used.
Intervention: Nipas application
Outcomes
Primary Outcomes
Influence of treatment on bacteria levels in wounds
Time Frame: 24 hours
The second part of the study was dedicated to analyzing the number of bacteria in tooth extraction wounds.
Intensity of pain vs. PRF and Nipas application
Time Frame: 24 hours
In order to evaluate the relationship between intensity of pain after application of PRF and Nipas, Numeric Rating Scale pain scale is used. NRS is a horizontal line with an eleven point numeric range. It is labeled from zero to ten, with zero being an example of someone with no pain and ten being the worst pain possible. The higher score means worse outcome in case of present study.