Cardiopulmonary Exercise Testing as an Outcome Predictor in Coronary Artery Bypass Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- Eduardo Tibirica, MD, PhD
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Mortality after cardiac surgery
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
This is a prospective cohort study of patients undergoing coronary artery bypass graft surgery. Prior to surgery, participants will undergo submaximal cardiopulmonary exercise testing on a treadmill. Participants will be followed for one month after surgery to assess mortality and non fatal complications.
Detailed Description
Coronary artery bypass surgery (CABG) is a complex and expensive procedure with great potential for morbidity and mortality. Preoperative evaluation is of paramount importance to optimize results. There is much evidence about the benefits of the cardiopulmonary exercise testing (CPET) in the evaluation of preoperative risk in non-cardiac surgeries. Thus, it is important to evaluate the relationship between parameters obtained in the CPET and the outcomes after cardiac surgery, especially CABG. This is a prospective cohort study in which participants undergo submaximal CEPT on a treadmill prior to CABG. Participants will be followed up for one month after surgery to assess mortality and non fatal complications. It is expected that poor cardiopulmonary fitness is related to worse outcomes in CABG, as already observed in other cardiac pathologies and in non-cardiac surgery.
Investigators
Eduardo Tibirica, MD, PhD
Senior Researcher
National Institute of Cardiology, Laranjeiras, Brazil
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing coronary artery bypass grafting surgery at the National Institute of Cardiology, Ministry of Health, Rio de Jnaeiro, Brazil.
Exclusion Criteria
- •Angina CCS IV, heart failure NYHA IV, inability to walk on a treadmill, severe left main coronary artery lesion.
Outcomes
Primary Outcomes
Mortality after cardiac surgery
Time Frame: 30 days
number of deaths during the first 30 days after cardiac surgery