Alzheimer Prevention Trials (APT) Webstudy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200,000
- 试验地点
- 1
- 主要终点
- Enrollment into Alzheimer's prevention research studies
研究概览
简要总结
The goal of the Alzheimer Prevention Trials (APT) Webstudy is to accelerate enrollment for Alzheimer's disease (AD) clinical trials by identifying and tracking individuals who may be at higher risk for developing AD dementia.
详细描述
The APT Webstudy will use web-based cognitive testing and questionnaires to generate a risk score which will be used to identify individuals who may be at an increased risk for developing AD dementia.
Individuals who join the APT Webstudy will register at https://www.aptwebstudy.org/, sign an electronic informed consent form (ICF), provide basic demographic information and participate in web-based cognitive testing. Participants will return the APT Webstudy quarterly (every 3 months) to complete the cognitive testing again.
Based on the risk score and changes identified in the cognitive testing results, participants will be invited to visit a partnering clinical trial site for an in-person visit with biomarker testing and clinical assessment.
The combined results of the web-based assessments, with the biomarker and clinical assessments, will allow an adaptive statistical algorithm to improve the selection of those at highest risk for developing AD.
To Join the APT Webstudy, please visit https://www.aptwebstudy.org/.
研究设计
- 研究类型
- 观察性
- 观察模型
- 其他
- 时间视角
- 其他
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- male or female at least 50 years of age
- no evidence of dementia
- willing to participate in remote longitudinal cognitive testing and possible referral for biomarker assessment based on risk
排除标准
- N/A. Anyone can register for the APT Webstudy, however, only individuals identified using the risk algorithm will be referred for in-person biomarker assessments.
结局指标
主要结局
Enrollment into Alzheimer's prevention research studies
时间窗: 5 years
次要结局
- Referral into prevention research studies(5 years)
- Number of individuals enrolled into Alzheimer's prevention studies(5 years)
研究者
研究点 (1)
标识符
- NCT 编号
- NCT03638583
- 其他研究编号
- HS-17-00746, R01AG053798
日期
- 首次提交
- (8年前)
- 首次发布
- (8年前)
- 主要完成日期
- (5个月前)
- 研究完成日期
- (5个月前)
- 最近核实
- 最近更新
- (去年)
监管与共享
- FDA 监管药物
- 否
- 个体参与者数据共享计划
- 否
- 是否有结果
- 否