To see how Methylene blue drug which is used to increase O2 saturation levels, is helpful in treating Covid 19 patients.
Not Applicable
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
- Registration Number
- CTRI/2021/04/033142
- Lead Sponsor
- DR SMITHA K S
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Confirmed case of Covid 19 (RT-PCR)
2) Admission to Intensive care unit
3) Sex-Males and Females
4) Age- 18 to 90 years old.
5) Need for Oxygen support ( HFNC, NIV)
6) Respiratory rate (RR) between 20 to 30
7) SpO2 between <=90 to 94 on room air.
8) PaO2/FiO2 <200-300
9) Written informed consent
Exclusion Criteria
Pregnancy and breastfeeding
2) History of G6PD deficiency
3) Severe renal insufficiency (GFR <30ml/min/1.73m2)
4) Medical records of Cirrhosis
5) Active or Chronic Hepatitis
6) History of allergy to Methylene blue
7) Patients on immunosuppressive agents.
8) Patients exposed to aniline dyes and Dapsone
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method