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3D CT Guidance for Transjugular Intrahepatic Portosystemic Shunt Creation

Not Applicable
Conditions
Portal Hypertension
Interventions
Device: CT-image guidance
Drug: CO2 portograms guidance
Registration Number
NCT02480426
Lead Sponsor
West China Hospital
Brief Summary

To prospectively evaluate the efficacy of real-time 3D CT-image guidance and CO2 portography during transjugular intrahepatic portosystemic shunt (TIPS) creation.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
15
Inclusion Criteria
  1. Cirrhosis
  2. Scheduled for indicated TIPS procedure
Exclusion Criteria
  1. Presence of portal vein thrombosis
  2. Presence of ascites
  3. Presence of hepatic vein occlusion or stenosis
  4. Proven malignancy including hepatocellular carcinoma 5. End-stage renal disease under renal replacement therapy; 6. Cardiorespiratory failure 7. Pregnancy or patients not giving informed consent for TIPS procedures

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
CT-image guidanceCT-image guidancePreviously acquired portal venous phase of CT datasets and intra-operative CT datasets were registered on a dedicated workstation. The selected volume of interest of the CT-image showing portal vein vasculature was overlaid onto the fluoroscopic display as real-time 3D CT-image guidance during the procedure.
CO2 portographyCO2 portograms guidancetwo two-dimensional (2D) CO2 portograms
Primary Outcome Measures
NameTimeMethod
Technical success rateprocedure
Secondary Outcome Measures
NameTimeMethod
Median needle passes for portal vein entryprocedure
The median radiation dose for the whole TIPS procedureprocedure
The rate of TIPS complication6 months
Median radiographic fluoroscopy time for portal vein entryprocedure
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