NCT03403127已完成不适用
Prospective Study of CT and PET Imaging During a Course of Radical Radiotherapy to Determine the Dosimetric Benefits of Re-Planning in Non-Small Cell Lung Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 主要终点
- GTV Volumes
研究概览
简要总结
This study will see whether the addition of more frequent planning CTs during the course of radiation, and of Positron Emission Tomography (PET), a diagnostic test similar to CT, prior to and during a course of radiation may provide information that could potentially be used during the treatment to improve the initial radiation plan.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age equal to or more than 18 years old
- •Patients with NSCLC consenting for radiotherapy to the primary tumor and / or mediastinal / hilar lymph nodes. Prescription doses should be 60Gy or higher.
- •Chemo-RT patients of any stage of NSCLC
- •Patients with a measurable tumor on CT scan.
- •Patients who are able to lie supine for two consecutive 25 minutes sessions.
排除标准
- •Trimodality patients who will have surgery within 2 months post RT
- •Previous radiotherapy to intended treatment volumes.
- •Patients with recurrent disease
- •Active malignancy other than lung cancer
- •Pregnancy
- •Failure to provide written informed consent
结局指标
主要结局
GTV Volumes
时间窗: 7 weeks post RT Treatment
The ratio of the GTV volumes defined using FDG PET (GTVPET) planning scans
GTV volumes
时间窗: 3 months post RT treatment
he ratio of the GTV volumes defined using 4D CT (GTV4DCT) planning scans is a prognostic parameter for NSCLC
次要结局
未报告次要终点
研究者
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