Evaluation of the effect of early BCG-vaccination on development of asthma and allergic rhinitis during childhood - follow-up study at age 7 years.
Completed
- Conditions
- asthma10001708hayfever
- Registration Number
- NL-OMON36994
- Lead Sponsor
- Kinderlongziekten
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 116
Inclusion Criteria
participation in study with code WOK 98-24, dd 01-02-1999
Exclusion Criteria
no participation in earlier study with code WOK 98-24
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Asthma, defined by periodic wheezing and dyspnoea, combined with a 9%<br /><br>reversibility in FEV1 and/or exhaled NO above 20 ppb.<br /><br>Allergic rhinitis. defined by periodic or perennial sneezing, runny or blocked<br /><br>nose when not having a cold or the flu.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Nitric oxide measurements in nasal air, specific IgE to allergens and<br /><br>immunologic parameters in serum.</p><br>