Coordination of trunk, head and arm movements during functional tasks, in healthy children and children with Duchenne muscular dystrophy, spinal muscular atrophy and cerebral palsy.

Completed

• Conditions: muscle diseases; Neuromuscular diseases; 10028302

• Registration Number: NL-OMON45000
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 71

Inclusion Criteria

- Between age of 6 and 20 years
- Able to show arm motor skills at request
- For patient groups: genetically confirmed diagnosis of Duchenne muscular dystrophy or clinically confirmed diagnosis of cerebral palsy

Exclusion Criteria

- Other disabling diseases affecting the trunk, head or arms
- Surgical scoliosis correction
- Participating in other studies at the same time

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameters will be the active range of trunk and head motion<br /><br>(e.g. motion in one direction), dynamic range of trunk and head motion (e.g.<br /><br>during functional arm tasks), maximal sEMG amplitude during movements as<br /><br>percentage of EMG amplitude in maximal voluntary contraction (MVC) and a trunk<br /><br>impairment classification score.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters will be the force and/or pressure profiles as<br /><br>parameters for balance and stability of the trunk, and for determination of the<br /><br>kinetics.</p><br>