Effects of Various Types of Ultrasound Therapy in Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Change in Knee Pain Intensity (VAS Score) Description: Pain intensity will be assessed using the 10-cm Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates worst imaginable pain. The
研究概览
简要总结
Knee osteoarthritis (KOA) is a degenerative joint condition characterized by degeneration, which is commonly attributed to the cumulative effects of mechanical stress and the slow deterioration of articular cartilage. KOA is a highly prevalent musculoskeletal disorder that affected 300 million people globally in 2017. It can affect any joint, although the most commonly affected are the knees, hands, hips, and spine
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 45 to 65 years.
- •Body mass index (BMI) 18.5-29.9 kg/m².
- •Diagnosis of knee osteoarthritis according to the American College of Rheumatology criteria.
- •Kellgren-Lawrence grade I-III.
排除标准
- •Rheumatologic conditions such as rheumatoid arthritis.
- •Prior knee surgery.
- •Previous lower-extremity fracture involving the knee joint.
- •Diabetes mellitus.
- •Neuropathy or sensory disorders.
- •Intra-articular corticosteroid injection or platelet-rich plasma treatment within the previous 6 months.
- •Thrombosis of the lower limbs.
- •Contraindications to therapeutic ultrasound, including open epiphysis, infection, cardiac disease, metal implants, pacemaker, pregnancy, or thrombophlebitis.
- •Wound or laceration in the soft tissues surrounding the knee.
- •Skin disease around the treatment area.
- •Use of pain medications during the study that could influence outcomes.
- •Knee physiotherapy within the previous 3 months.
- •Other knee procedures, including aspiration or knee arthroplasty.
结局指标
主要结局
Change in Knee Pain Intensity (VAS Score) Description: Pain intensity will be assessed using the 10-cm Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates worst imaginable pain. The
时间窗: Baseline and after 12 weeks of intervention
Pain intensity will be assessed using the 10-cm Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates worst imaginable pain. The primary outcome is the change in VAS score from baseline to
The Western Ontario and McMaster Universities Arthritis Index (WOMAC)
时间窗: Baseline and after 12 weeks of intervention
The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) will be used to evaluate pain, stiffness, and physical function. The total score ranges from 0 to 96, with higher scores indicating worse symptoms. The outcome is the change in total score from baseline to post-treatment.
Change in Knee Joint Range of Motion (ROM)
时间窗: Baseline and after 12 weeks of intervention
Knee flexion and extension range of motion will be measured using a standard universal goniometer. The outcome is the change in degrees of motion from baseline to post-treatment.
次要结局
未报告次要终点
研究者
Ehab A. Abdallah
Associate Professor of Orthopedic Physical Therapy
Horus University