Study on utility of a cognitive function test program

Not Applicable

• Conditions: Alzheimer's disease, mild cognitive impairment

• Registration Number: JPRN-jRCTs042200006
• Lead Sponsor: Takechi Hajime

Brief Summary

For verifying the usefulness of the program, A-003 for diagnostic support, the measurement of 20 persons each of healthy control(HC), mild cognitive impairment(MCI), and mild Alzheimer's disease(AD1) was carried out. The 'total score A' was strongly correlated with MMSE or MoCA-J and the 'total score A' showed higher discriminant accuracy between HC and MCI+AD1. These results indicate that A-003 has validity and efficacy in discriminating early cognitive decline.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-04-27
• Study Completion: 2022-09-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

1. Subjects who sign an informed consent
2. subjects who can manipulate a tablet
3. outpatient and medication are not asked.
4. A statistically significant difference is not observed in terms of things like an age between groups.
(1) Alzheimers disease
- Subjects who are diagnosed with diagnostic guidelines for Alzheimers disease from the National Institute on Aging-Alzheimers Association workgroups where assessment for decline of cognitive function is carried out with the ADNI criteria.
- Subjects who are certainly diagnosed after first visit.
(2) mild cognitive impairment
- Subjects who are diagnosed with diagnostic guidelines mild cognitive impairment due to Alzheimers disease from the National Institute on Aging-Alzheimers Association workgroups where assessment for decline of cognitive function is carried out with the ADNI criteria.
- Subjects who are certainly diagnosed after first visit.
(3) healthy volunteer
- Subjects who are finally diagnosed to be healthy after assessment.
- Subjects who accompany outpatients.

Exclusion Criteria

- Subjects with psychiatric disorders like major depression disorder, bipolar disorder, epilepsy or schizophrenia
- Subjects who may have epilepsy or photosensitivity by light stimulation
- Subjects who are judged to be unacceptable by medical doctors

Study & Design

• Study Type: Interventional
• Study Design: Not specified