Effect of Salba & Flax on Postprandial Glycemia and Subjective Satiety

Phase 1

Completed

• Conditions: Hyperglycemia, Postprandial
• Interventions: Dietary Supplement: Salba; Dietary Supplement: Control; Dietary Supplement: Flax

• Registration Number: NCT02621307
• Lead Sponsor: Unity Health Toronto

Brief Summary

The purpose of this study is to determine whether drinks containing Salvia hispanica L (Salba) or Flax lower postprandial blood glucose levels and improve appetite in healthy individuals.

Detailed Description

Dietary fibre has been implicated in improving many risk factors associated with Type 2 Diabetes and Cardiovascular Disease (CVD). However, on average, Norther Americans consume less than half of the recommended amount set by health agencies. It has been proposed that the health benefits of dietary fibre may be attritbuted to rheological characteristics such as viscosity. Salvia hispanica L (Salba) and Flax are nutritionally similar. The primary objective of this research trial is to study the effects of Salba and Flax on postprandial glycemia and appetite in healthy individuals.

Study Timeline

• Study Start: 2010-07
• Primary Completion: 2011-07
• Study Completion: 2011-07
• Status Verified: 2015-11
• Study First Submitted: 2015-11-27
• Study First Submitted QC: 2015-12-01
• Last Update Submitted: 2015-12-01
• Study First Posted: 2015-12-03
• Last Update Posted: 2015-12-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• BMI less than 35 kg/m^2

Exclusion Criteria

• known history of liver or kidney disease, diabetes, hypertension, stroke, or myocardial infarctions, thyroid disease, gastrointestinal disease, or AIDS
• subjects using medications or Natural Health Products

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Salba	Salba	50g glucose 25g ground Salba (Salba Corporation Ltd, Buenos Aires, Argentina) 200ml water
Control	Control	50g glucose 200ml water
Flax	Flax	50g glucose 31g ground Flax (Bob's Red Mill Natural Raw Whole Flaxseed) 200ml water

Primary Outcome Measures

Name	Time	Method
Change in Postprandial Blood Glucose	2 Hours	At each visit, postprandial blood glucose will be measured via capillary blood samples, at 15, 30, 45, 60, 90, and 120 minutes after intake of test meals

Secondary Outcome Measures

Name	Time	Method
Change in Subjective Satiety	2 Hours	At each visit, subjective satiety (how hungry/full you feel) will be measured via questionnaires, at 15, 30, 45, 60, 90, and 120 minutes after intake of test meals

Trial Locations

Locations (1)

St. Michael's Hospital; 🇨🇦 Toronto, Ontario, Canada