Effect of Topical Oil Melilotus officinalis on primary knee Osteoarthritis versus Diclofenac gel
- Conditions
- Primary osteoarthrit.Primary generalized (osteo)arthrosis M15.0
- Registration Number
- IRCT2016082129461N1
- Lead Sponsor
- niversity of Welfare and Rehabilitation Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
60 years old and older ?pain at least in one knee over the last 3 months? Weak to moderate osteoarthritis (grade 1 to 3 based on criteria) Kellegren-Lawrence (K-L) grading scale? The existence of moderate pain, with minimum galling, according to VAS, at least for four weeks before entering the random assignment
Exclusion criteria:
Sensitivity, and allergies, to Melilotus officinalis vegetable oil and Diclofenac gel? Skin lesion in the knee area? Secondary osteoarthritis in the rheumatic diseases such as rheumatoid arthritis, gout, septic arthritis, metabolic arthritis, traumatic arthritis? Patients who had joint replacement with surgery ? Using from oral and local, steroids, within 14 days before study? Injecting the, intra-articular steroid within 90 days before study? Alcoholism, and addiction to drugs? Having radiculopathy and neuropathy
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improve of Physical Activity. Timepoint: in beginning of intervention; 2 and 4 week after beginningintervention. Method of measurement: questionnaire.
- Secondary Outcome Measures
Name Time Method Decrease of pain. Timepoint: beginning of intervention; 2 and 4 week after beginningin tervention. Method of measurement: questionnaire.