Effect of Lotion of Myrtus communts and Phyllanthus emblica on the Androgenic Alopecia

Phase 3

Conditions: Androgenic alopecia.
Androgenic alopecia

Registration Number: IRCT20230808059082N1

Lead Sponsor: Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 120

Inclusion Criteria

Females in the pre-menopausal period complaining of hair loss
Patient consent to participate and fill out the informed consent form.

Exclusion Criteria

History of allergic response/hypersensitivity to any ingredients and pharmaceutical products.
History of thyroid disorder, diabetes mellitus, polycystic ovary syndrome
Subjects under medical treatment for hair problems, consuming drugs (such as minoxidil, finasteride, platelet rich plasma or Biotin) and laser therapy in the 2 months prior to the study
Subjects under medical treatment for hair problems with 5 a-reductase inhibitors.
Subjects under medical treatment with antiandrogenic agents (such as spironolactone, cimetidine and cyproterone acetate) in the 2 months prior to the study
Subjects consuming systemic corticosteroid therapy for more than 14 days in the 2 months prior to the study
Any active scalp disease in the 6 months prior to the study
Any history of cancer or autoimmune diseases
History of hair transplant
Pregnancy or Brest - feeding
History of serious acute illness in the 2 months prior to the study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hair count (number of hairs in 0.7 cm2). Timepoint: Week 8, week 16. Method of measurement: Trichoscan method.;Hair density (number of hairs in cm2). Timepoint: Week 8, week 16. Method of measurement: Trichoscan method.;Hair diameter. Timepoint: Week 8, week 16. Method of measurement: Trichoscan method.;Ratio of anagen to telogen. Timepoint: week8, week16. Method of measurement: Trichoscan method.

Secondary Outcome Measures

Name	Time	Method
Dandruff. Timepoint: Before and after study (week1, week16). Method of measurement: Patient view assessment (5 Likert).;Greasy hair. Timepoint: Before and after study (week1, week16). Method of measurement: Patient view assessment(5 Likert).