A Randomised Controlled Feasibility Study of a Novel Technology-assisted Home Based Aerobic Exercise Programme for Individuals With Parkinson's Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- Tan Tock Seng Hospital
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Adherence to exercise program
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
This study aim to evaluate the (1) feasibility of a novel mobile application ( Combat PD) that support a home-based gamified aerobic exercise program in individuals with mild Parkinson's disease (PD).
The study aims to further explore (2) the effectiveness of Combat PD in improving adherence to prescribed home-based exercise program; and (3) the clinical effectiveness if combat PD in improving motor and non-motor function in PD.
Detailed Description
This study aim to evaluate the (1) feasibility of a novel mobile application ( Combat PD) that support a home-based gamified aerobic exercise program in individuals with mild Parkinson's disease (PD). The study aims to further explore (2) the effectiveness of Combat PD in improving adherence to prescribed home-based exercise program; and (3) the clinical effectiveness if combat PD in improving motor and non-motor function in PD.
Investigators
Chloe Chung Lau Ha
Principal Physiotherapist
Tan Tock Seng Hospital
Eligibility Criteria
Inclusion Criteria
- •Aged 30-75, diagnosed with Parkinson's disease, with mild disease severity (Hoehn and Yahr stages I to II)
- •Sedentary lifestyle
- •Receive a stable dose of dopaminergic medication for at least 4 weeks prior to study inclusion
- •Has a smart phone device
Exclusion Criteria
- •Uncontrolled hypertension, arrhythmia, or unstable cardiovascular status
- •Poorly controlled diabetes mellitus
- •Advanced kidney disease
- •Recent cerebrovascular event/ concussion/ fall in the last 6 months
- •Significant cognitive impairment (MoCA\<21)
- •Any other medical/orthopaedic/psychiatric condition that would interfere with ability to participate in the study
- •No stable internet or smart device access
- •Inability to fill up self-reported questionnaires
- •Attendance at any regular exercise programme up to 4 weeks prior to study inclusion
Outcomes
Primary Outcomes
Adherence to exercise program
Time Frame: 12 weeks
actual exercise intensity (period of exercise performed within prescribed heart rate zone), compared to prescribed exercise targets.
Secondary Outcomes
- Dual-task Timed Up and Go Test (TUG)(12 weeks)
- Montreal Cognitive Assessment (MoCA)(12 weeks)
- Scales for Outcomes in Parkinson's disease (SCOPA-sleep)(12 weeks)
- Timed Up and Go test (TUG)(12 weeks)
- Adverse events(12 weeks)
- Motor section of Movement Disorder Society sponsored Unified Parkinson's disease Rating Scale (MDS-UPDRS-III)(12 weeks)
- 6-minute walk test(12 weeks)
- Fatigue Severity Scale (FSS)(12 weeks)
- Parkinson Disease Questionnaire (PDQ)-8(12 weeks)
- Hospital Anxiety and Depression Scale (HADS)(12 weeks)