Observing Physiological Changes in Patients With Long-term Oxygen Therapy Via Optical and Accelerometry Signals
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Respiratory Disease
- Sponsor
- Insel Gruppe AG, University Hospital Bern
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- SpO2 changes from before and during LTOT
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
In this project, the investigators aim to assess changes of physiological parameters obtained non-invasively through PPG and accelerometry signals between before and during LTOT (long-term oxygen therapy) and investigate if those changes are different in patients with worsening frailty and/or improving quality of life.
For this, they will record optical (PPG) and accelerometry data via a datalogger on 40 patients undergoing LTOT and assess the PPG-derived physiological signals.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age ≥ 18-year-old, and
- •Chronic respiratory disease including a) chronic obstructive pulmonary disease, b) interstitial lung disease, c) pulmonary hypertension, d) bronchiectasis, and
- •Prescribed new LTOT due to a chronic respiratory disease with resting and/or exertional hypoxemia, and
- •Able to speak/read/understand German or French, and
- •Willing and able to understand and provide signed informed consent
Exclusion Criteria
- •Pregnant or lactating women, or
- •Inability to follow the procedures/instructions of the study (e.g. due to language, psychological disorders, dementia, etc.), or
- •Patients having a subordination link to the investigators, or
- •Patients with isolated nocturnal oxygen therapy or LTOT prescription for a heart disease, sleep associated breathing disorder, neuromuscular disease or lung cancer, or
- •Known participation in another human research project (ClinO/HRO) that may affect the objectives of this study.
Outcomes
Primary Outcomes
SpO2 changes from before and during LTOT
Time Frame: From 1 week before start of LTOT to 1 month after start of LTOT
Record SpO2 (%) to compare before and during LTOT
Respiratory rate changes from before and during LTOT
Time Frame: From 1 week before start of LTOT to 1 month after start of LTOT
Record respiratory rate (breaths per minute) to compare before and during LTOT
Heart rate changes from before and during LTOT
Time Frame: From 1 week before start of LTOT to 1 month after start of LTOT
Record heart rate (BPM) to compare before and during LTOT