Observing Physiological Changes in Patients With Long-term Oxygen Therapy Via Optical and Accelerometry Signals
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- SpO2 changes from before and during LTOT
研究概览
简要总结
In this project, the investigators aim to assess changes of physiological parameters obtained non-invasively through PPG and accelerometry signals between before and during LTOT (long-term oxygen therapy) and investigate if those changes are different in patients with worsening frailty and/or improving quality of life.
For this, they will record optical (PPG) and accelerometry data via a datalogger on 40 patients undergoing LTOT and assess the PPG-derived physiological signals.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18-year-old, and
- •Chronic respiratory disease including a) chronic obstructive pulmonary disease, b) interstitial lung disease, c) pulmonary hypertension, d) bronchiectasis, and
- •Prescribed new LTOT due to a chronic respiratory disease with resting and/or exertional hypoxemia, and
- •Able to speak/read/understand German or French, and
- •Willing and able to understand and provide signed informed consent
排除标准
- •Pregnant or lactating women, or
- •Inability to follow the procedures/instructions of the study (e.g. due to language, psychological disorders, dementia, etc.), or
- •Patients having a subordination link to the investigators, or
- •Patients with isolated nocturnal oxygen therapy or LTOT prescription for a heart disease, sleep associated breathing disorder, neuromuscular disease or lung cancer, or
- •Known participation in another human research project (ClinO/HRO) that may affect the objectives of this study.
结局指标
主要结局
SpO2 changes from before and during LTOT
时间窗: From 1 week before start of LTOT to 1 month after start of LTOT
Record SpO2 (%) to compare before and during LTOT
Respiratory rate changes from before and during LTOT
时间窗: From 1 week before start of LTOT to 1 month after start of LTOT
Record respiratory rate (breaths per minute) to compare before and during LTOT
Heart rate changes from before and during LTOT
时间窗: From 1 week before start of LTOT to 1 month after start of LTOT
Record heart rate (BPM) to compare before and during LTOT
次要结局
未报告次要终点