NCT00390507已完成4 期
Modification of Posttetanic Count (PTC) for Monitoring Deep Neuromuscular Block II
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 4
- 主要终点
- Time to first response to TOF stimulation (T1)
研究概览
简要总结
The purpose of this study is to examine the relationship between post-tetanic count (PTC) and time to first response to Train of four (TOF) stimulation during deep neuromuscular blockade induced by rocuronium.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •General anaesthesia >1 hour
- •Surgery in supine position with possibility of monitoring the neuromuscular blockade at the thumb (n.ulnaris stimulation).
- •Written informed content
排除标准
- •Neuromuscular disorders, hepatic and renal dysfunction
- •Medication expected to interfere with the neuromuscular blocking agent
- •Allergy to any medication used during anaesthesia
- •Body weight less or exceeding 20% of the ideal body weight
- •Pregnancy or breastfeeding
结局指标
主要结局
Time to first response to TOF stimulation (T1)
次要结局
- Time to TOF 1.0
- Time to second response to TOF stimulation (T2)
- Time to first post-tetanic count (PTC)
- Number of post-tetanic count at first response to TOF
- Time to T1=25%
- Interval 25-75%
- Time to TOF 0.9
研究者
研究点 (4)
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