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Clinical Trials/NCT02187965
NCT02187965
Completed
Not Applicable

Impact of Muscle Fat Accumulation on the Genomic Profile of Skeletal Muscle in Older Adults

Purdue University1 site in 1 country11 target enrollmentStarted: August 2011Last updated:
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ConditionsIntermuscular Adipose Tissue Quantification

Overview

Phase
Not Applicable
Status
Completed
Enrollment
11
Locations
1
Primary Endpoint
MRI
OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Overview

Brief Summary

Subjects were asked to come to the Purdue facilities after an overnight fast on 2 different testing days for 2.5 hours each day. On one day the subjects participated in blood pressure and body weight measurements as well as a muscle biopsy from the thigh. On the second day the subjects underwent an MRI and MRS scan of the thigh and calf.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
60 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •60-80 years old, men and women, normal body weight or obese,

Exclusion Criteria

  • •Certain medical conditions could have placed them at risk

Outcomes

Primary Outcomes

MRI

Time Frame: 1 day

To determine the within day reproducibility of MRI scans for intermuscular adipose tissue (IMAT) quantification in older men and women.

Secondary Outcomes

  • genomic profile(1 day)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Wayne Campbell

Professor

Purdue University

Study Sites (1)

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