Use of Stereolithographic Model in Tooth Autotransplantation and Periodontal Ligament Stem Cells for Pulp Revascularization and Reinnervation to Increase the Success Rate for Tooth Replacement in Children

Universitaire Ziekenhuizen KU Leuven1 site in 1 country100 target enrollmentMay 2013

ConditionsIncrease Success Rate of Tooth Transplantation

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Increase Success Rate of Tooth Transplantation
Sponsor: Universitaire Ziekenhuizen KU Leuven
Enrollment: 100
Locations: 1
Primary Endpoint: survival rate
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this study lies in comparing the outcome of the proposed technique in a large sample size group to the outcome of the conventional tooth autotransplantation method and to provide sufficient evidence for improving the long-term success rate of the tooth autotransplantation procedure.

Registry

clinicaltrials.gov

Start Date

May 2013

End Date

December 2017

Last Updated

4 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Universitaire Ziekenhuizen KU Leuven

Responsible Party

Principal Investigator

Reinhilde Jacobs

Prof. Dr.

Universitaire Ziekenhuizen KU Leuven

Eligibility Criteria

Inclusion Criteria

•The subjects will be divided in two groups according to different surgical protocols.
•Pediatric subjects (age between 9-18 years) treated with the CBCT-based replica procedure (prospective approach).
•Pediatric subjects (N=50) that missed their teeth due to agenesis or lost their permanent teeth due to trauma, caries, and endodontic failure and referred to dentistry department for replacement of the missing tooth by means of tooth autotransplantation.
•Pediatric subjects (age between 9-18 years) treated with the conventional method (prospective and retrospective).
•Pediatric subjects (N=50) that missed their teeth due to agenesis or lost their permanent teeth due to trauma, caries, and endodontic failure and referred to dentistry department for replacement of the missing tooth by means of tooth autotransplantation.
•A matched control patient will be selected with the focus on a very similar surgical challenge, based on age, gender and a matching donor tooth with the same stage of root development and host bed.