Skip to main content
Clinical Trials/NCT01854307
NCT01854307
Terminated
Not Applicable

The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements

Haukeland University Hospital1 site in 1 country5 target enrollmentMay 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pneumoperitoneum
Sponsor
Haukeland University Hospital
Enrollment
5
Locations
1
Primary Endpoint
Change of stroke volume variation and pulse pressure variation during pneumoperitoneum
Status
Terminated
Last Updated
10 years ago

Overview

Brief Summary

Perioperative goal directed fluid therapy may reduce complication rate after surgery. Minimal invasive cardiac output monitoring is a key method to guide fluid therapy. More operations are being performed by keyhole surgery (laparoscopy). For laparoscopy, the abdomen is filled with carbon dioxide. Increased pressure in the abdomen may influence minimal cardiac output monitoring, therefore minimal cardiac output monitoring is not recommended during laparoscopy. This study aims to validate minimal cardiac output monitoring during laparoscopy and therefore facilitate for goal directed fluid therapy.

Registry
clinicaltrials.gov
Start Date
May 2013
End Date
August 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Single Group
Sex
Male

Investigators

Sponsor
Haukeland University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Ib Jammer

MD

Haukeland University Hospital

Eligibility Criteria

Inclusion Criteria

  • all patients \>18 years scheduled for robot-assisted prostatectomy
  • able to give informed consent

Exclusion Criteria

  • Patient with atrial fibrillation or other non-regular rhythm.
  • Severe aorta/mitral stenosis
  • Not able to give informed consent

Outcomes

Primary Outcomes

Change of stroke volume variation and pulse pressure variation during pneumoperitoneum

Time Frame: peroperative

Change in PPV/SVV(LiDCO), PPV(Philips) and SVV/CO(TEE) in percent before and after pneumoperitoneum.

Secondary Outcomes

  • Effect of fluid bolus under pneumoperitoneum (responder vs. non-responder)(peroperative)
  • Difference in measurements from different methods of minimal cardiac output monitoring.(peroperative)

Study Sites (1)

Loading locations...

Similar Trials