The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 5
- 试验地点
- 2
- 主要终点
- Change of stroke volume variation and pulse pressure variation during pneumoperitoneum
研究概览
简要总结
Perioperative goal directed fluid therapy may reduce complication rate after surgery. Minimal invasive cardiac output monitoring is a key method to guide fluid therapy. More operations are being performed by keyhole surgery (laparoscopy). For laparoscopy, the abdomen is filled with carbon dioxide. Increased pressure in the abdomen may influence minimal cardiac output monitoring, therefore minimal cardiac output monitoring is not recommended during laparoscopy. This study aims to validate minimal cardiac output monitoring during laparoscopy and therefore facilitate for goal directed fluid therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •all patients >18 years scheduled for robot-assisted prostatectomy
- •able to give informed consent
排除标准
- •Patient with atrial fibrillation or other non-regular rhythm.
- •Severe aorta/mitral stenosis
- •Not able to give informed consent
结局指标
主要结局
Change of stroke volume variation and pulse pressure variation during pneumoperitoneum
时间窗: peroperative
Change in PPV/SVV(LiDCO), PPV(Philips) and SVV/CO(TEE) in percent before and after pneumoperitoneum.
次要结局
- Effect of fluid bolus under pneumoperitoneum (responder vs. non-responder)(peroperative)
- Difference in measurements from different methods of minimal cardiac output monitoring.(peroperative)
研究者
Ib Jammer
MD
Haukeland University Hospital