Comparison the effect of magnesium sulfate with pregabalin on prevention of the pain severity induced by remifentanil.
Not Applicable
Recruiting
- Conditions
- Postoperative pain management following rhinoplasty..Other acute postprocedural painG89.18
- Registration Number
- IRCT20121204011662N12
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 105
Inclusion Criteria
A total of 105 patients in the ASA class 1 who candidate for rhinoplasty will be enrolled in the study.
Exclusion Criteria
Exclusion criteria : History of the heart diseases , pulmonary diseases, liver diseases, kidney diseases, neurological and psychological disease, history of the allergy to drugs such as pregabalin, magnesium sulfate, remifentanil, history of alcohol and narcotics abuse, patients who suffering from chronic pain, those who used pain killer drugs 72 hours prior to anesthesia.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of postoperative pain. Timepoint: In the first 6 hours postoperation, every hour and then 24 hours after operation. Method of measurement: Numerical Rating Scale.
- Secondary Outcome Measures
Name Time Method Sedation Score. Timepoint: In the first 6 hours postoperation, every hour and then 24 hours after operation. Method of measurement: Ramsey Scale.;Incidence of nausea and vomiting. Timepoint: In the first 6 hours postoperation, every hour and then 24 hours after operation. Method of measurement: 0: No nausea and vomiting, 1: Nuasea without Vomiting, 2: Both Nausea and Vomiting.