Microvascular Recovery in Acute MI, a single center, prospective, randomized, single blind parallel-group comparison of sonothrombolysis versus standard of care performed after (post) coronary reperfusion (primary PCI). - MRUSMI

VU University Medical Center (VUmc)0 个研究点目标入组 60 人开始时间: 2019年8月20日最近更新: 2019年11月25日

适应症

试验速览

暂无简介。

•Patients presenting with STEMI with:
•- = 2mm ST-segment elevation in 2 anterior or lateral leads; or
•- = 1 mm ST-segment elevation in 2 inferior leads
•- = 1mm ST-segment elevation in lateral leads (I, aVL, V5, V6)
•- Persistence of ST-elevation of more than 30% after PCI in the lead with the highest ST-elevation on the ECG after PCI compared to the ECG before PCI
•- Within 12 hours of symptom onset
•- Age = 30 years
•- Adequate apical and/or parasternal images by echocardiography
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 30
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range 30

•-Previous coronary bypass surgery
•-Cardiogenic shock
•-Known or suspected hypersensitivity to ultrasound contrast agent used for the study
•-Life expectancy of less than two months or terminally ill
•-Known bleeding diathesis or contraindication to glycoprotein IIB/IIIA inhibitors, anticoagulants or aspirin
•-Known large right to left intracardiac shunts

发起方

VU University Medical Center (VUmc)