NCT00397683终止2 期
Proprietary Information - Exploratory (Non-Confirmatory) Trial
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 终止
- 入组人数
- 2
- 试验地点
- 20
- 主要终点
- Proprietary Information - Exploratory (Non-Confirmatory) Trial
研究概览
简要总结
The purpose of this study is to test MK0822 on disease activity in patients with osteoarthritis in the knee. Disease modifying activity of MK0822 will be assessed by measurements of knee cartilage using Magnetic Resonance Imaging (MRI) of the knee.
This is an early phase trial and some specific protocol information is proprietary and not publicly available at this time. (Full information is available to trial participants).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with symptomatic knee osteoarthritis for at least 6 months based on clinical and radiographic criteria
- •Patients should be in general good health and must have a certain level of knee pain or be taking pain medicines on most days
- •Specific radiographic (X-ray) and MRI features must also be satisfied
排除标准
- •Non-osteoarthritic causes of knee pain
- •Ineligibility to undergo MRI of the knee due to patient tolerability or safety reasons
- •Previous septic arthritis, tibial osteotomy or knee replacement in both knees
- •Acute injury of knee ligaments or meniscus in past 2 years
- •Knee arthroscopy in past 12 months
- •Anticipated arthroscopy or surgery in next 18 months
- •Use of intra-articular injections of hyaluronan (e.g. Hyalgan (TM), Synvisc (TM), Orthovisc (TM)) in past 6 months, or injections of glucocorticoids (e.g. Kenalog (TM), Aristospan (TM), Depo-Medrol (TM)) in past 3 months or anticipated knee injections during the study
- •Glucosamine or chondroitin sulfate are allowable if they are at a stable dose for past 3 months and will continue at that dose during the study
- •Other exclusion criteria apply-Please ask the study doctor for details
结局指标
主要结局
Proprietary Information - Exploratory (Non-Confirmatory) Trial
次要结局
- Proprietary Information - Exploratory (Non-Confirmatory) Trial
研究者
研究点 (20)
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