Postexercise Hot-Water Immersion on Exercise Performance in Hypoxia
- Conditions
- Heat ExposureExercise Training
- Registration Number
- NCT06672614
- Lead Sponsor
- Nipissing University
- Brief Summary
The purpose of this study is to determine the effect of 5 days post-exercise hot water immersion on exercise performance at simulated altitude.
- Detailed Description
Human performance is compromised at altitude due to a lower partial pressure of oxygen and subsequent reductions in the convective transport of oxygen to tissue. Long-term acclimation to attitude incurs physiological adaptations that result in a near return to sea-level performance; however, the time required (\~2 weeks) for such adaptations is often logistically challenging for athletes, military personnel or other individuals who reside at sea level. Recent research suggests that physiological acclimation to heat stress (i.e., heat acclimation) and altitude (i.e., hypoxia) share similar cellular adaptations, namely an up-regulation of Hypoxia-inducible factor 1 (HIF-1) and various heat shock proteins. Therefore, it is hypothesized that heat acclimation may provide physiological protection from reduced oxygen transport to the tissue and enhance performance at altitude. This cross-tolerance model is supported by traditional heat acclimation protocols (i.e., submaximal exercise in hot ambient temperature); however, it has not been tested with passive exposure to heat stress through post-exercise hot water immersion.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 20
- Physically active (minimum of 90 minutes of moderate-intensity exercise per week)
- Cardiovascular disease
- resident of >1500 m above sea-level in the past year;
- history of fainting
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Time-Trial Performance in hypoxia conditions 30 minutes Results of a 16 km time-trial test conducted at an fraction of inspired oxygen (FiO2) of 0.14
- Secondary Outcome Measures
Name Time Method Heart Rate during exercise 90 minutes Heart rate will be measured throughout the time trial tests and exercise training interventions using a wireless (Polar) heart rate chest strap.
Skin temperature during exercise 90 minutes Skin temperature measured throughout the time trial-tests and exercise training intervention using temperature probes attached to the calf, thigh, chest and arm, from which weighted averages are calculated.
Core temperature during exercise 90 minutes Core body temperature measured throughout the time-trial tests and exercise training interventions using a rectal temperature probe.
Pulse oxygen saturation during exercise 30 minutes Capillary oxygen saturation measured on the earlobe throughout the time-trial tests using pulse oximetry.
Trial Locations
- Locations (1)
Nipissing University
🇨🇦North Bay, Ontario, Canada