Comparison of Multiparametric Prostate MRI and Ga-68 PSMA PET Imaging in Prostate Cancer Staging

Not Applicable

• Conditions: Prostate Cancer Stage; Prostate Cancer

• Registration Number: NCT05427864
• Lead Sponsor: Gulhane Training and Research Hospital

Brief Summary

In this study, it is aimed to compare the lesion location, lesion size, local and distant metastases detection rates of Ga68 PSMA PET and Multiparametric Prostate MR imaging tests used in staging in patients diagnosed with prostate cancer.

The pathologies of the patients who were decided to undergo radical prostatectomy as a treatment will also be compared with the staging tests.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-01
• Status Verified: 2022-06
• Study First Submitted: 2022-06-11
• Study First Submitted QC: 2022-06-19
• Study First Posted: 2022-06-22
• Last Update Submitted: 2022-06-25
• Last Update Posted: 2022-06-28
• Primary Completion: 2023-01-05
• Study Completion: 2023-03-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 47

Inclusion Criteria

• diagnosed with prostate cancer
• Gleason score 7 or above / 6 with high risk
• No other treatment

Exclusion Criteria

• treated with radiotherapy
• treated with ADT

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Lesion location	Between prostate biopsy and curative treatment decision , usually 2 month	Both MRI and PET results will be compared. Lesion location will be defined as "left", "right", "apical", "basal", "midline".
Extraprostatic involvement	Between prostate biopsy and curative treatment decision , usually 2 month	Both MRI and PET results will be compared. Involvement will be stated as "exist" , "non-exist".
Lesion Size	Between prostate biopsy and curative treatment decision , usually 2 month	Both MRI and PET results will be compared, Lesion size will be stated in milimeters.
Local and distant metastasis	Between prostate biopsy and curative treatment decision , usually 2 month	Both MRI and PET results will be compared. Metastasis will be stated as "exist" , "non-exist".
Lymph node involvement	Between prostate biopsy and curative treatment decision , usually 2 month	Both MRI and PET results will be compared. Involvement will be stated as "exist", "non-exist".

Trial Locations

Locations (1)

Gulhane Research and Training Hospital; 🇹🇷 Ankara, Etlik, Turkey