Efficacy of the MovinCog Intervention in Children: A Randomized, Placebo-controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Learning Disorders
- Sponsor
- University of Auckland, New Zealand
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Change from baseline working memory capacity at 10 weeks
- Last Updated
- 5 years ago
Overview
Brief Summary
This study aims to test the efficacy of the MovinCog Intervention to enhance cognitive abilities in children 7-15 yrs. The intervention consists of two parts: a physical exercise regimen, based on high-intensity training, and a cognitive training component. The design will contrast the intervention with an active control group, matched for expectancy effects.
Detailed Description
Specifically, the investigators will compare both components together (exercise and cognitive training) against either one of the components (exercise alone, or cognitive training alone) and against an active control group. The study will include measures of scholastic aptitude, as well as of working memory and cognitive control (primary outcome measures), two cognitive abilities that are critical to daily life activities, and that respond well to training. In addition, the investigators will measure physiological responses to training, to monitor changes associated with exercise (secondary outcome measures). Finally, the investigators will relate training-specific improvements with transfer gains, to better model the interaction between training and transfer. This will provide a comprehensive understanding of the dynamics associated with the intervention.
Investigators
David Moreau
PhD
University of Auckland, New Zealand
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Age outside inclusion criteria
- •History of seizures, brain trauma
Outcomes
Primary Outcomes
Change from baseline working memory capacity at 10 weeks
Time Frame: Baseline and 10-week posttest
Constructs measured by multiple tasks (bds, corsi, n-back)
Change from baseline cognitive control at 10 weeks
Time Frame: Baseline and 10-week posttest
Constructs measured by multiple tasks (flanker, go/no-go, stroop)
Change from baseline scholastic aptitude at 10 weeks
Time Frame: Baseline and 10-week posttest
Constructs measured by multiple national (New Zealand), standardized tests
Secondary Outcomes
- BDNF polymorphism measured by genetic saliva kit(Baseline)
- Change from baseline resting heart rate at 10 weeks(Baseline and 10-week posttest)