Efficacy of the MovinCog Intervention in Children

Not Applicable

• Conditions: Learning Disabilities; Learning Disorders; Cognitive Change

• Registration Number: NCT03255499
• Lead Sponsor: University of Auckland, New Zealand

Brief Summary

This study aims to test the efficacy of the MovinCog Intervention to enhance cognitive abilities in children 7-15 yrs. The intervention consists of two parts: a physical exercise regimen, based on high-intensity training, and a cognitive training component. The design will contrast the intervention with an active control group, matched for expectancy effects.

Detailed Description

Specifically, the investigators will compare both components together (exercise and cognitive training) against either one of the components (exercise alone, or cognitive training alone) and against an active control group. The study will include measures of scholastic aptitude, as well as of working memory and cognitive control (primary outcome measures), two cognitive abilities that are critical to daily life activities, and that respond well to training. In addition, the investigators will measure physiological responses to training, to monitor changes associated with exercise (secondary outcome measures). Finally, the investigators will relate training-specific improvements with transfer gains, to better model the interaction between training and transfer. This will provide a comprehensive understanding of the dynamics associated with the intervention.

Study Timeline

• Study First Submitted: 2017-08-11
• Study First Submitted QC: 2017-08-16
• Study First Posted: 2017-08-21
• Study Start: 2017-09-10
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-05
• Last Update Posted: 2020-11-09
• Primary Completion: 2021-12-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Age 7-15

Exclusion Criteria

• Age outside inclusion criteria
• History of seizures, brain trauma

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change from baseline working memory capacity at 10 weeks	Baseline and 10-week posttest	Constructs measured by multiple tasks (bds, corsi, n-back)
Change from baseline cognitive control at 10 weeks	Baseline and 10-week posttest	Constructs measured by multiple tasks (flanker, go/no-go, stroop)
Change from baseline scholastic aptitude at 10 weeks	Baseline and 10-week posttest	Constructs measured by multiple national (New Zealand), standardized tests

Secondary Outcome Measures

Name	Time	Method
BDNF polymorphism measured by genetic saliva kit	Baseline	Effect of BDNF polymorphism on primary outcomes
Change from baseline resting heart rate at 10 weeks	Baseline and 10-week posttest	Measured by monitor

Trial Locations

Locations (1)

University of Auckland; 🇳🇿 Auckland, New Zealand