NCT02317237已完成3 期
Anaesthetic Strategy During Endovascular Therapy: General Anaesthesia or Conscious Sedation ?
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 128
- 试验地点
- 2
- 主要终点
- Growth of DWI lesion
研究概览
简要总结
Patients suffering a stroke with a large vessel occlusion is often treated intra veneous thrombolyse and on top of that also intra arterial therapy. It is unknown what form of anaestesia is best during intra arterial therapy. The investigators will randomize these patients between general anaestesia and local anaestesia. Outcome will be growth of the ischemic lesion as judged on an MRI scan.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •NIHSS>10
- •groin puncture<6hours from stroke onset
- •occlusion of ICA, ICA-T, M1, M2
排除标准
- •MRI contraindications
- •intubated prior to arrival
- •posterior circulation stroke
- •allergy to anestetics
结局指标
主要结局
Growth of DWI lesion
时间窗: 48-72 hours
次要结局
- Time from arrival to groin puncture and recanalization(1-2 hours)
- Blood pressure during intervention(1-2 hours)
- Modified Rankin Score(90 days)
研究者
研究点 (2)
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