Anaesthesiological Routine Care for Thrombectomy in Cerebral Ischaemia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,500
- 试验地点
- 1
- 主要终点
- Neurological outcome 90 days after the stroke
研究概览
简要总结
Endovascular thrombectomy is the standard of care for acute ischaemic stroke due to large-vessel occlusion. Current guidelines for periprocedural anaesthesiological care give gross recommendations on management of stroke patients during recanalization, but lack detailed information.
To determine how anaesthesiologists support endovascular thrombectomy with regard to anaesthetic technique, choice of substances, haemodynamic management, and ventilation. With a multivariate analysis, the investigators will look for the factors of anesthetic management that are independently correlated with a good or bad outcome.
详细描述
see brief summary
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Endovascular stroke treatment involving anaesthesia care
排除标准
- •In-hospital onset of stroke
- •Inclusion in an interventional study concerning the anaesthesia protocol
- •Age under 18 years
结局指标
主要结局
Neurological outcome 90 days after the stroke
时间窗: 90 days
Neurological outcome is measured using the modified Rankin Scale \[0-6\], with higher values indicating worse outcome. As a Primary Outcome Measure, the scale will be dichotomized into good (modified Rankin Scale ≤ 2) versus poor (modified Rankin Scale \> 2) outcome.
次要结局
- Grade of recanalization(sixty minutes)
- Proportion of patients breathing spontaneously(sixty minutes)
- Mortality(90 days)
- Duration(30 Minutes)