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Clinical Trials/NCT05928026
NCT05928026
Completed
N/A

Financial Support in an Underserved and Low-Income Population With Heart Failure

University of Texas Southwestern Medical Center1 site in 1 country153 target enrollmentJune 9, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Heart Failure, Systolic
Sponsor
University of Texas Southwestern Medical Center
Enrollment
153
Locations
1
Primary Endpoint
Heart Failure Quality of Life by Kansas City Cardiomyopathy Questionnaire (KCCQ)
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

The goal of this clinical trial is to test whether financial support in the form of a one-time $500 stipend would improve medication adherence and quality of life in low-income, socially-needy patients with heart failure with reduced ejection fraction in the post-discharge setting. The main questions it aims to answer are:

  • Will financial support improve heart failure quality of life?
  • Will financial support improve medication adherence?

Participants will complete surveys on quality of life, social stress, and spending habits at their baseline visit. Participants will be randomly assigned to receive $500 at their baseline visit or $0 at their baseline visit. At their one month visit, quality of life and medication adherence will be assessed. These results will be compared between groups. The group that received $0 at their baseline visit will be provided $500 at their one-month visit and return for a two-month visit. At that visit, quality of life and medication adherence will be assessed. These results will be compared to their one-month results.

Researchers will compare the 1-month quality of life scores and medication adherence scores between the immediate financial support vs delayed financial support. Researchers will also compare 1-month vs 2-month quality of life and adherence data for participants who were randomized to the delayed financial support group.

Registry
clinicaltrials.gov
Start Date
June 9, 2023
End Date
May 1, 2025
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ambarish Pandey

Assistant Professor of Internal Medicine

University of Texas Southwestern Medical Center

Eligibility Criteria

Inclusion Criteria

  • Age \> 18
  • English speaking participants who completed SOCIAL-HF study surveys
  • Ejection Fraction \<=40% and eligible for at least one component of GDMT
  • Has at least some difficulty paying monthly bills (Somewhat Difficult and Very Difficult)
  • Annual household income \<130% Federal Poverty Limit
  • Have at least two additional social needs based on the following domains:
  • Cost-related nonadherence
  • Food Insecurity
  • Housing Instability
  • Transportation Difficulty

Exclusion Criteria

  • Unwilling to return for 1 and 2-month follow-up visits.
  • Currently in jail or prison
  • Primary residence outside Dallas County
  • Legal Blindness
  • Systolic blood pressure \<90 mmHg on screening
  • Contraindications or Intolerance all medications available for therapeutic drug monitoring (metoprolol, losartan, lisinopril, valsartan, and spironolactone)
  • Unable to answer orientation questions.

Outcomes

Primary Outcomes

Heart Failure Quality of Life by Kansas City Cardiomyopathy Questionnaire (KCCQ)

Time Frame: 2 months

Quality of life will be ascertained using the KCCQ-12, a validated measure of quality of life among patients with heart failure. The score contains four domains, physical limitation, symptom frequency, quality of life, and social limitations. Each subdomain provides an individual score from 0 to 100, with 0 denoting the worst and 100 denoting the best possible health. These scores are averaged and presented as a summary score.

Secondary Outcomes

  • Self-reported medication adherence by Morisky Medication Adherence Scale(2 months)
  • Change in social stress(2 months)
  • Detection of Serum Levels of Guideline Directed Medical Therapies (GDMT)(2 months)

Study Sites (1)

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