Effects of Transversus Abdominis Plane Block on Recovery Quality and Maternal-Neonatal Outcomes After Cesarean Delivery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 83
- 试验地点
- 2
- 主要终点
- VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity ( Time to first rescue analgesia requirement and number of patients and total dosage of flurbiprofen axetil used within 48 hours postoperatively;
研究概览
简要总结
ltrasound-guided transversus abdominis plane (TAP) block is an emerging local anesthesia technique that effectively alleviates postoperative pain by injecting anesthetic drugs around the nerves in the abdominal wall. Compared with traditional analgesic methods, TAP blockade may have better analgesic effects and fewer side effects. However, current research on the application of TAP blockade after cesarean section is still limited. Therefore, this study will systematically evaluate its actual effectiveness in pain management after cesarean section through a prospective randomized controlled trial
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Aged 20-40 years, in good general health
- •ASA physical status I-II
- •Singleton, term (37-41 weeks) pregnancy with normal fetal development
- •Planned for elective cesarean section, no labor
排除标准
- •Pregnancy complications (e.g., severe preeclampsia, gestational diabetes, placental abruption)
- •Major organ dysfunction (heart, liver, kidney) or psychiatric history
- •Allergy to local anesthetics or any study drugs
- •Prior abdominal surgery or infection that may affect block efficacy
- •Coagulation disorders or current anticoagulant use
- •Refusal to participate or inability to comply with follow-up
研究组 & 干预措施
TAP Block Group
The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg + tropisetron 8 mg);
干预措施: The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg) (Drug)
the control group
received only the same formula intravenous analgesia pump. For both groups, rescue
结局指标
主要结局
VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity ( Time to first rescue analgesia requirement and number of patients and total dosage of flurbiprofen axetil used within 48 hours postoperatively;
时间窗: 5 months
VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity (coughing or turning) at 2, 6, 12, 24, and 48 hours postoperatively were recorded by anesthesiologists not involved in this study.
次要结局
未报告次要终点
研究者
Qing Yuan
Shandong Provincial Maternal and Child Health Care Hospital
Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University