The Prognostic Value of Anion Gap in Predicting Major Adverse Cardiovascular Events Among Patients With ST-Segment Elevation Myocardial Infarction

Recruiting

• Conditions: ST-segment Elevation Myocardial Infarction (STEMI)
• Interventions: Diagnostic Test: Anion gap

• Registration Number: NCT06586424
• Lead Sponsor: Universitas Diponegoro

Brief Summary

This study aims to evaluate the prognostic value of the anion gap in predicting major adverse cardiovascular events among patients with ST-segment elevation myocardial infarction. Researchers will collect information based on hospital registry as secondary data of in patient who had diagnosed as ST-segment elevation myocardial infarction and underwent primary percutaneous coronary intervention. The data consist of demographic data, clinical presentation, laboratory, and angiography result were collected from hospital registry by reviewing medical record. Then, the data was analyzed by using IBM SPSS Statistics v26.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-01
• Primary Completion: 2024-06-30
• Study First Submitted: 2024-08-31
• Status Verified: 2024-09
• Study First Submitted QC: 2024-09-03
• Last Update Submitted: 2024-09-03
• Study First Posted: 2024-09-06
• Last Update Posted: 2024-09-06
• Study Completion: 2024-10-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Adults with 18 - 70 years old with diagnosis of STEMI who underwent PPCI

Exclusion Criteria

• History of heart failure due to any causes
• Cardiogenic shock before PPCI
• Any infection at the time of presentation
• Pregnant woman
• Other causes of high anion gap levels such as chronic kidney disease, metabolic acidosis, etc

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
MACE group	Anion gap	Patient with STEMI who suffered major adverse cardiovascular events (MACE) after underwent primary percutaneous coronary intervention (PPCI)

Primary Outcome Measures

Name	Time	Method
Major Adverse Cardiovascular Events (MACE)	During hospitalization, up to 1 weeks

Secondary Outcome Measures

Name	Time	Method
Incidence of mortality	During hospitalization, up to 1 weeks
Incidence of reinfarction	During hospitalization, up to 1 weeks
Incidence of stroke	During hospitalization, up to 1 weeks
Incidence of lethal arrhythmia	During hospitalization, up to 1 weeks
Incidence of acute lung oedema	During hospitalization, up to 1 weeks
Incidence of cardiogenic shock	During hospitalization, up to 1 weeks

Trial Locations

Locations (1)

Dr. Kariadi Central General Hospital; 🇮🇩 Semarang, Central Of Java, Indonesia