Prospective study of midazolam for preventing postoperative nausea and vomiting in patients following laparoscopic benign gynecological surgery
Not Applicable
- Conditions
- Not Applicable
- Registration Number
- KCT0002930
- Lead Sponsor
- Bundang CHA General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Female
- Target Recruitment
- 144
Inclusion Criteria
Adults of American Society of Anesthesiologists’ physical status 1 or 2 undergoing laparoscopic gynaecological
surgery, Age of 19-65
Exclusion Criteria
Adults of American Society of Anesthesiologists’ physical status 3 or more, who have allergy with ondansetron or midazolam, who had history of taken chemotherapy, chronic use of opioids or alcohol.
Decreased liver or kidney function, conversion to open surgery
pregnancy or breast-feeding, obesity
Patients with diabetes mellitus or gastrointestinal disease, and those who had taken an antiemetic medication 24 h before surgery
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete response up to 48 h after surgery. Complete response was defined as no PONV and no rescue antiemetics
- Secondary Outcome Measures
Name Time Method incidence of nausea, incidence of severe nausea (mild (1–3), moderate (4–6), and severe (7–10)), incidence of vomiting, additional use of rescue antiemetics