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Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis

Not Applicable
Not yet recruiting
Conditions
Joint Pain
Registration Number
NCT06864390
Lead Sponsor
Ain Shams University
Brief Summary

The goal of this clinical trial is to compare the efficiency and efficacy of genicular nerves blockade by chemical phenol neurolysis versus radiofrequency ablation in managing pain in patients suffering from grade IV KOA in term of NRS pain score.

The participants will be evaluated by numeric rating scale and oxford knee score for assessment of pain relief up to 16 weeks.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
114
Inclusion Criteria
  • Grade 4 knee osteoarthritis according to Kellgren-Lawrence radiological classification.
  • Failure to manage pain with conservative methods.
Exclusion Criteria
  • Prior knee replacement
  • Patients with cardiac pacemakers or implantable cardiac defibrillators.
  • Septic knee or systemic sepsis.
  • Allergy to any of the drugs used in the study.
  • Coagulopathy or patients on anticoagulants.
  • Patients with psychiatric illness.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Numeric rating scalebaseline, 2, 4, 8,12 and 16 weeks after the procedure

By an independent physician pain will be recorded using numeric rating scale which is a screening tool used to assess pain severity using a 0 - 10 scale with zero meaning no pain and 10 meaning the worst pain ever.

Secondary Outcome Measures
NameTimeMethod
oxford knee scorebaseline, 4, 8, 12, 16 weeks after the procedure

This score is used to assess both function and pain of the knee on a scale ranging from 0 (worst pain and function) and 48 (best function and no pain) this score will be recorded by an independent physician

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