Calcitonin Gene-Related Peptide (CGRP) in patients with migraine and endometriosis

• Conditions: N80.9; G43.0; Migraine without aura [common migraine]; Endometriosis, unspecified

• Registration Number: DRKS00020744
• Lead Sponsor: Charité Campus Charité Mitte

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-12
• Study Completion: 2020-06-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 125

Inclusion Criteria

diagnosed migraine according to the International Headache Society (IHS) criteria
- laparoscopically diagnosed endometriosis

Exclusion Criteria

- age < 18 or > 60 years;
- other known headache disorders
- current intake of a migraine prophylactic medication
- unregular or absent menstrual cycle (e.g. pregnancy, post-menopausal, hormonal contraception, sterilisation).

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference in the CGRP plasma concentrations between d2 and d15 of menstrual cycle in patients with migraine and endometriosis (compared to patients with migraine only, endometriosis only, and healthy controls)

Secondary Outcome Measures

Name	Time	Method
CGRP plasma concentrations at d2 and d15 of menstrual cycle in patients with migraine and endometriosis (compared with patients with migraine only, endometriosis only, and healthy controls)