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临床试验/CTRI/2025/11/097467
CTRI/2025/11/097467尚未招募不适用

ROLE OF MAGNETIC RESONANCE IMAGING IN EVALUATION OF INTRA CRANIAL INFECTIONS

Jawaharlal Nehru Medical College,Sawangi(Meghe),Wardha,442001,Maharashtra1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2025年12月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
44
试验地点
1
主要终点
MRI was undoubtedly an indispensable tool to

研究概览

简要总结

This prospective cross-sectional study aims to assess the role of MRI in the evaluation of intracranial infections, which remain a major health concern in India due to their high prevalence, non-specific presentations, and frequent diagnostic delays. A total of 44 patients with clinical suspicion of intracranial infections will undergo MRI using both conventional sequences (T1, T2, FLAIR) and advanced techniques such as diffusion-weighted imaging (DWI), susceptibility-weighted imaging (SWI), and post-contrast studies to evaluate parenchymal, meningeal, and vascular involvement. The study objectives are to describe MRI characteristics of various infections, document clinical presentations, identify imaging predictors of poor prognosis, and correlate radiological findings with CSF analysis. By integrating clinical and imaging data, this study seeks to highlight MRI as a critical non-invasive tool for early diagnosis, prognostication, and treatment planning in intracranial infections, particularly in resource-limited settings.

研究设计

研究类型
Observational

入排标准

年龄范围
0.00 Day(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • Patients of all age groups with clinical suspicion of intracranial infection.
  • Willingness to undergo MRI examination.

排除标准

  • Patients who do not give consent.
  • Contraindications to MRI or gadolinium-based contrast agents Patients suffering from claustrophobia.

结局指标

主要结局

MRI was undoubtedly an indispensable tool to

时间窗: 8 weeks

evaluate patients presenting with intracranial

时间窗: 8 weeks

infections. Most of the cases were pathognomonic

时间窗: 8 weeks

in imaging appearance; while some required

时间窗: 8 weeks

clinico-laboratory correlation. Careful evaluation

时间窗: 8 weeks

of MR behaviour of infectious lesions helped in

时间窗: 8 weeks

identifying not only the precise location and

时间窗: 8 weeks

extent of the lesion, but also in proposing a

时间窗: 8 weeks

specific etiology in many such patients.

时间窗: 8 weeks

次要结局

未报告次要终点

研究者

发起方
Jawaharlal Nehru Medical College,Sawangi(Meghe),Wardha,442001,Maharashtra
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Utkarsh Kaura

Jawaharlal Nehru Medical College, Sawangi(Meghe), Wardha, Maharastra

研究点 (1)

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